Discussion on Modern Progress and Research Methods of Human Chromosome High Resolution

Abstract

Progress Since Yunis and Sanchez obtained high-resolution prophase chromosomes by incubation with low-concentration colchicamide and cold, high-resolution banding has made great progress in methodology, nomenclature standardization, and popularization and application. The progress of methodology is reflected in the emergence of a variety of methods and variations for preparing high-resolution banding specimens. These methods can be divided into two