HOW FAR HAVE WE PROGRESSED IN ORAL DRUG DELIVERY SYSTEM: AN UPDATE

Abstract

INTRODUCTION 
Drug targeting to specific organs and tissues is the one of the most important part of a treatment, 
as they help in providing the best treatment outcome whilst maintaining an optimal therapeutic 
dose and eliminating the side effects/complications associated with it. Herein, our paper provides 
an insight on the various advancements in local target therapies related to common oral 
manifestations of microbial infections and immunological diseases associated with oral medicine 
& therapeutics.
MATERIALS AND METHODS
40 drug delivery system articles associated with oral mucosal lesions and vesiculo-bullous lesions
published within the time frame of 2008-2017 were selected which consisted of 5 case reports, 15 
research articles & 20 review articles (narrative, meta-analysis and systematic reviews).
CONCLUSIONS
Novel technological advancements in amalgamation with effective formulation helps to overcome 
these shortcomings, that are observed in the conventional form of drug administration whilst 
integrating such novel techniques with the current techniques; to improve the patients’ quality of 
life; be it in the systemic or in the topical form.